Heart Regeneration with Engineered Myocardial Tissue
نویسندگان
چکیده
منابع مشابه
Engineered heart tissue for regeneration of diseased hearts.
Cardiac tissue engineering aims at providing contractile heart muscle constructs for replacement therapy in vivo. At present, most cardiac tissue engineering attempts utilize heart cells from embryonic chicken and neonatal rats and scaffold materials. Over the past years our group has developed a novel technique to engineer collagen/matrigel-based cardiac muscle constructs, which we termed engi...
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Currently-used mechanical and biological heart valve prostheses have several disadvantages. Mechanical prostheses, based on carbon, metallic and polymeric components, require permanent anticoagulation treatment, and their usage often leads to adverse reactions, e.g. thromboembolic complications and endocarditis. Xenogenous and allogenous biological prostheses are associated with immune reaction...
متن کاملRecent advances in tissue-engineered corneal regeneration
Eun Young Kim1), Jeong Eun Song1), Chan Hum Park2), Choun-Ki Joo3) and Gilson Khang1,*) 1)Department of PolymerNano Science & Technology, Department of BIN Fusion Technology and Polymer BIN Fusion Research Center, Chonbuk National University, Jeonju, Korea 2)Department of Otorhinolaryngology-Head and Neck Surgery, Chuncheon Sacred Heart Hospital, College of Medicine, Hallym University, Gangwon,...
متن کاملThick acellular heart extracellular matrix with inherent vasculature: a potential platform for myocardial tissue regeneration.
The decellularization of porcine heart tissue offers many opportunities for the production of physiologically relevant myocardial mimetic scaffolds. Earlier, we reported the successful isolation of a thin porcine cardiac extracellular matrix (pcECM) exhibiting relevant bio-mechanical properties for myocardial tissue engineering. Nevertheless, since native cardiac tissue is much thicker, such th...
متن کاملEarly in vivo experience with tissue-engineered trileaflet heart valves.
BACKGROUND Tissue engineering is a new approach in which techniques are being developed to transplant autologous cells onto biodegradable scaffolds to ultimately form new functional autologous tissue. Workers at our laboratory have focused on tissue engineering of heart valves. The present study was designed to evaluate the implantation of a whole trileaflet tissue-engineered heart valve in the...
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ژورنال
عنوان ژورنال: Annual Review of Biomedical Engineering
سال: 2014
ISSN: 1523-9829,1545-4274
DOI: 10.1146/annurev-bioeng-071812-152344